Cogentin is metabolized by which enzyme?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $9.99Unlock all

Study for the HIV/AIDS and Antiretroviral Therapy Test. Utilize flashcards and multiple choice questions, each detailed with hints and answers. Prepare efficiently for your examination!

Multiple Choice

Cogentin is metabolized by which enzyme?

Explanation:
Cogentin is cleared mainly through the liver by the cytochrome P450 system, with CYP2D6 being the primary enzyme responsible for metabolizing benztropine. This means that a person’s CYP2D6 activity, which can vary genetically, directly affects how quickly benztropine is broken down. Inhibitors of CYP2D6 can slow its metabolism, increasing drug exposure and the potential for anticholinergic side effects. That’s why CYP2D6 is the best answer: it represents the main metabolic pathway for this drug.

Cogentin is cleared mainly through the liver by the cytochrome P450 system, with CYP2D6 being the primary enzyme responsible for metabolizing benztropine. This means that a person’s CYP2D6 activity, which can vary genetically, directly affects how quickly benztropine is broken down. Inhibitors of CYP2D6 can slow its metabolism, increasing drug exposure and the potential for anticholinergic side effects. That’s why CYP2D6 is the best answer: it represents the main metabolic pathway for this drug.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy