Nausea and vomiting medications include which drug?

Nausea and vomiting medications include which drug?

• A. Chlorpromazine
• B. Trifluoperazine
• C. Haloperidol
• D. Pimozide

Answer: (A)

Blocking dopamine D2 receptors in the chemoreceptor trigger zone reduces the vomiting reflex, so drugs that antagonize these receptors are effective antiemetics. Chlorpromazine, a phenothiazine, is a classic antiemetic because it reliably blocks D2 receptors in the CTZ, dampening nausea signals before they reach the vomiting center. While other dopamine antagonists can also contribute to antiemetic effects, chlorpromazine is the one most traditionally used and specifically recognized for treating nausea and vomiting. Side effects from this class (and from chlorpromazine in particular) include sedation, hypotension, and extrapyramidal symptoms, so monitoring is important.

Blocking dopamine D2 receptors in the chemoreceptor trigger zone reduces the vomiting reflex, so drugs that antagonize these receptors are effective antiemetics. Chlorpromazine, a phenothiazine, is a classic antiemetic because it reliably blocks D2 receptors in the CTZ, dampening nausea signals before they reach the vomiting center. While other dopamine antagonists can also contribute to antiemetic effects, chlorpromazine is the one most traditionally used and specifically recognized for treating nausea and vomiting. Side effects from this class (and from chlorpromazine in particular) include sedation, hypotension, and extrapyramidal symptoms, so monitoring is important.